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The Study at a Glance Who was studied: 132 children and adolescents aged 1017 with type 2 diabetes Duration: 52 weeks (with the primary endpoint measured at week 26) Design: Randomized, double-blind, placebo-controlled Drug: Oral semaglutide at once-daily doses of 3 mg, 7 mg, or 14 mg Background therapy: Participants continued on metformin, basal insulin, or both The Results The trial met its primary endpoint
Remarkably we discovered that monotremes evolved an alternative mechanism to degrade GLP-1
NICE recommends GLP-1 receptor agonists in specific circumstances, such as when metformin is contraindicated or not tolerated, or as an add-on therapy
The biggest practical difference between a pill and a shot comes down to one word: absorption
Patients should engage in regular follow-ups with their healthcare provider to assess the effectiveness of the treatment and make necessary adjustments, ensuring that the benefits outweigh any potential risks over time
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